Hsa_circ_0006006 is a potential biomarker for prognosis and cisplatin resistance in non-small cell lung cancer
NSCLC survival prognosis is associated with aberrant expression of hsa_circ_0006006, which regulates NSCLC cell proliferation and apoptosis and thus promotes DDP drug resistance. These findings provide potential targets for patient prognosis and assessment of biomarkers of response to DDP therapies that can be used to aid in early diagnosis and prognostic assessment, as well as new options for the future development of relevant small-molecule inhibitors or nucleic acid drugs.
Authors
- Xiaona Li (ORCID: https://orcid.org/0009-0000-1596-5348)
- Min Ding (ORCID: https://orcid.org/0000-0001-7355-9786)
- Jing Zhao (ORCID: https://orcid.org/0000-0003-2205-1581)
Institutions
- Second Military Medical University (CN)
- Tongren Hospital (CN)
- Wuhan Third Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-03-08
- DOI
- https://doi.org/10.1186/s41065-025-00392-w
- Citations
- 3
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.42