Antibacterial Activity of Keben (Barringtonia Asiatica L.) Leaf Extract on the Growth of Bacteria Staphylococcus Epidermis and Pseudomonas Aureginosa

The use of antibiotics is very high. Antibiotics or antimicrobial drugs can be sourced from synthetic or natural / herbal ingredients. Keben leaves are one of the plants that have antibacterial properties because of their chemical content. This study aimed to determine the antibacterial activity of methanol, ethyl acetate, and n-hexane extracts from keben leaves (Barringtonia asiatica) against Staphylococcus epidermal and Pseudomonas aureginosa bacteria. The method used is the paper disc diffusion method with a concentration of 20%, 40%, and 60% keben leaf extract. The results of the antibacterial activity test of methanol, ethyl acetate, and n-hexane extracts of keben leaves against Staphylococcus epidermal bacteria with concentrations of 20%, 40%, and 60% resulted in an inhibition zone diameter of 7.65 mm -17.48 mm, while in Pseudomonas aureginosa bacteria produces an inhibition zone diameter of 7.65 mm – 12.73 mm. the 20% and 40% n-Hexan extract had no inhibition zone and the 20% methanol extract had no inhibition zone. Based on the results of research, keben leaves have the potential as an antibacterial.