Physiological Scaffold Remodeling in the Coronary Artery After 30 Months of Bioadaptor Implantation

The DynamX Bioadaptor (Elixir Medical Corporation) is a novel coronary artery scaffold consisting of 3 helical strands connected by a bioabsorbable polymer. After 6 months, the polymer dissolves, restoring the physiological motion of the coronary artery as the interconnected (caged) structure of the scaffold disengages. Here we report the cases of 2 patients treated with the Bioadaptor who underwent intravascular imaging at the time of the index procedure and during follow-up periods of 30 and 36 months, respectively. The cross-sectional images of the scaffold were analyzed and compared with those obtained during the index procedure. At follow-up, the mean cross-sectional area of the scaffold was increased significantly in both cases, regardless of the degree of intimal hyperplasia. Such unique properties of the Bioadaptor make it a promising alternative to contemporary drug-eluting stents.

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Publication Details

Journal
JACC Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1016/j.jaccas.2024.103089
Citations
3
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
6.02
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article

Physiological Scaffold Remodeling in the Coronary Artery After 30 Months of Bioadaptor Implantation

Shiori Kawakami, Takeshi Yamada, Akihiko Takahashi, Shunsuke Nakajima et al.
3 citations
JACC Case Reports
Coronary Interventions and Diagnostics
6.02
article

Physiological Scaffold Remodeling in the Coronary Artery After 30 Months of Bioadaptor Implantation

Shiori Kawakami, Takeshi Yamada, Akihiko Takahashi, Shunsuke Nakajima, Norimasa Taniguchi, Shigeru Saito, Tetsuya Hata
article en
3 citations

Abstract

The DynamX Bioadaptor (Elixir Medical Corporation) is a novel coronary artery scaffold consisting of 3 helical strands connected by a bioabsorbable polymer. After 6 months, the polymer dissolves, restoring the physiological motion of the coronary artery as the interconnected (caged) structure of the scaffold disengages. Here we report the cases of 2 patients treated with the Bioadaptor who underwent intravascular imaging at the time of the index procedure and during follow-up periods of 30 and 36 months, respectively. The cross-sectional images of the scaffold were analyzed and compared with those obtained during the index procedure. At follow-up, the mean cross-sectional area of the scaffold was increased significantly in both cases, regardless of the degree of intimal hyperplasia. Such unique properties of the Bioadaptor make it a promising alternative to contemporary drug-eluting stents.

JACC Case ReportsVol. 30(5)
Kobe Asahi Hospital (JP), Shonan Kamakura General Hospital (JP)
Openalex Percentile: Top 5%
Coronary Interventions and Diagnostics
6.02
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