116P A novel cytoband-mediated copy number alteration model for predicting clinical outcomes among pan-cancer
Copy number alterations (CNAs) have emerged as promising biomarkers for predicting prognosis and therapeutic response in cancer. However, integrating CNA data from diverse gene panel-based sequencing platforms has posed a considerable challenge. This study aimed to develop a novel cytoband-mediated CNA algorithm capable of reliably predicting outcomes across multiple cancer types, no matter what gene panel was used.
Authors
- Aya El Helali (ORCID: https://orcid.org/0000-0001-6427-114X)
- Dingyuan Wang (ORCID: https://orcid.org/0000-0002-4858-6253)
- Bin Zhang (ORCID: https://orcid.org/0000-0003-4530-772X)
- Weiwei Dai (ORCID: https://orcid.org/0000-0003-3375-0249)
- Eunhee Ko
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.esmoop.2025.104277
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00