116P A novel cytoband-mediated copy number alteration model for predicting clinical outcomes among pan-cancer

Copy number alterations (CNAs) have emerged as promising biomarkers for predicting prognosis and therapeutic response in cancer. However, integrating CNA data from diverse gene panel-based sequencing platforms has posed a considerable challenge. This study aimed to develop a novel cytoband-mediated CNA algorithm capable of reliably predicting outcomes across multiple cancer types, no matter what gene panel was used.

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Publication Details

Journal
ESMO Open
Published
2025-03-01
DOI
https://doi.org/10.1016/j.esmoop.2025.104277
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

116P A novel cytoband-mediated copy number alteration model for predicting clinical outcomes among pan-cancer

Aya El Helali, Dingyuan Wang, Bin Zhang, Weiwei Dai et al.
ESMO Open
Cancer Genomics and Diagnostics
article

116P A novel cytoband-mediated copy number alteration model for predicting clinical outcomes among pan-cancer

Aya El Helali, Dingyuan Wang, Bin Zhang, Weiwei Dai, Eunhee Ko
article en

Abstract

Copy number alterations (CNAs) have emerged as promising biomarkers for predicting prognosis and therapeutic response in cancer. However, integrating CNA data from diverse gene panel-based sequencing platforms has posed a considerable challenge. This study aimed to develop a novel cytoband-mediated CNA algorithm capable of reliably predicting outcomes across multiple cancer types, no matter what gene panel was used.

ESMO OpenVol. 10
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), University of Hong Kong (HK)
Openalex Percentile: Top 95%
Cancer Genomics and Diagnostics
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