Heart Transplantation in a Patient With Liddle Syndrome

Liddle syndrome is characterized by hypertension, hypokalemia, and metabolic alkalosis. This paper presents the case of a 29-year-old man with Liddle syndrome complicated by stage D heart failure and stage 4 chronic kidney disease. Despite appropriate management, this patient developed refractory cardiogenic shock, ultimately requiring mechanical circulatory support with venoarterial extracorporeal membrane oxygenation and expedited heart transplant listing.

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Publication Details

Journal
JACC Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1016/j.jaccas.2024.103079
Primary Topic
Glycogen Storage Diseases and Myoclonus
Type
article
Field-Weighted Citation Impact
0.00
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article

Heart Transplantation in a Patient With Liddle Syndrome

Aparna Sajja, Avery E Calhoun, Jay Gohri, Kunal Bhatt et al.
JACC Case Reports
Glycogen Storage Diseases and Myoclonus
article

Heart Transplantation in a Patient With Liddle Syndrome

Aparna Sajja, Avery E Calhoun, Jay Gohri, Kunal Bhatt, Rahul Bakhle
article en

Abstract

Liddle syndrome is characterized by hypertension, hypokalemia, and metabolic alkalosis. This paper presents the case of a 29-year-old man with Liddle syndrome complicated by stage D heart failure and stage 4 chronic kidney disease. Despite appropriate management, this patient developed refractory cardiogenic shock, ultimately requiring mechanical circulatory support with venoarterial extracorporeal membrane oxygenation and expedited heart transplant listing.

JACC Case ReportsVol. 30(5)
Emory University (US), Sir Sayajirao General Hospital Medical College (IN), JSS Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 94%
Glycogen Storage Diseases and Myoclonus
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Heart Transplantation in a Patient With Liddle Syndrome — Aparna Sajja, Avery E Calhoun, et al. · JACC Case Reports (2025) | TGRS Research Map | TGRS