The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium
Childhood and adolescent HDL-C were prospectively and inversely associated with adult ASCVD, suggesting that low HDL-C could be a risk maker of adult ASCVD. Future replications, mechanistic studies and Mendelian randomisations on childhood HDL-C may clarify its causal effects on adult ASCVD.
Authors
- Markus Juonala (ORCID: https://orcid.org/0000-0001-9498-364X)
- Alison Venn (ORCID: https://orcid.org/0000-0001-7090-1398)
- Mika A. P. Kähönen (ORCID: https://orcid.org/0000-0002-4510-7341)
- Alan R. Sinaiko (ORCID: https://orcid.org/0000-0001-8277-3493)
- Elaine M. Urbina (ORCID: https://orcid.org/0000-0002-5640-6777)
- Lydia Bazzano (ORCID: https://orcid.org/0000-0002-8958-1352)
- Rema Ramakrishnan (ORCID: https://orcid.org/0000-0002-6784-8319)
- David R. Jacobs (ORCID: https://orcid.org/0000-0002-7232-0543)
- Noora Kartiosuo (ORCID: https://orcid.org/0000-0001-7859-0483)
- Jing Wang (ORCID: https://orcid.org/0000-0001-5701-476X)
- Olli Tuomas Raitakari (ORCID: https://orcid.org/0000-0001-9365-3702)
- Terence Dwyer (ORCID: https://orcid.org/0000-0002-2091-7663)
- Stephen R. Daniels (ORCID: https://orcid.org/0000-0001-5520-6952)
- Jorma S.A. Viikari (ORCID: https://orcid.org/0000-0001-6452-010X)
- Jessica Graus Woo (ORCID: https://orcid.org/0000-0003-3644-8432)
- Julia Steinberger (ORCID: https://orcid.org/0000-0002-2892-8594)
- Costan G. Magnussen (ORCID: https://orcid.org/0000-0002-6238-5730)
Institutions
- Tulane University (US)
- Cincinnati Children's Hospital Medical Center (US)
- University of Tasmania (AU)
- University of Minnesota (US)
- Royal Children's Hospital (AU)
- Baker Heart and Diabetes Institute (AU)
- University of Turku (FI)
- Turku University of Applied Sciences (FI)
- The University of Melbourne (AU)
- Turku University Hospital (FI)
- John Radcliffe Hospital (GB)
- University of Oxford (GB)
- Children's Hospital Colorado (US)
- Tampere University Hospital (FI)
- MNGI Digestive Health (US)
- Tampere University (FI)
- University of Minnesota Medical Center (US)
- Science Oxford (GB)
- Murdoch Children's Research Institute (AU)
- University of Cincinnati (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1093/eurjpc/zwaf117
- Citations
- 6
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 8.33