Expression of co-signaling molecules TIM-3/Galectin-9 at the maternal-fetal interface

The research results suggest that Galectin-9 and TIM-3, as important immune co-signaling molecules, may play a crucial role in maintaining the immune-tolerant microenvironment at the maternal-fetal interface. Additionally, the association between decidualization and Galectin-9 expression reveals its potential role in pregnancy maintenance, providing new insights for the study of adverse pregnancy outcomes.

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Publication Details

Journal
Placenta
Published
2025-03-05
DOI
https://doi.org/10.1016/j.placenta.2025.03.002
Citations
3
Primary Topic
Galectins and Cancer Biology
Type
article
Field-Weighted Citation Impact
2.39
Controls
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article

Expression of co-signaling molecules TIM-3/Galectin-9 at the maternal-fetal interface

Li Li, Xuqing He, Sujuan Zhang, Penghao Li et al.
3 citations
Placenta
Galectins and Cancer Biology
2.39
article

Expression of co-signaling molecules TIM-3/Galectin-9 at the maternal-fetal interface

Li Li, Xuqing He, Sujuan Zhang, Penghao Li, Jingliang Xu
article en
3 citations

Abstract

The research results suggest that Galectin-9 and TIM-3, as important immune co-signaling molecules, may play a crucial role in maintaining the immune-tolerant microenvironment at the maternal-fetal interface. Additionally, the association between decidualization and Galectin-9 expression reveals its potential role in pregnancy maintenance, providing new insights for the study of adverse pregnancy outcomes.

PlacentaVol. 163
Shantou University (CN), Chengdu Women's and Children's Central Hospital (CN), Shantou University Medical College (CN)
Zero hunger
Openalex Percentile: Top 12%
Galectins and Cancer Biology
2.39
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