Adverse drug reactions and contributing factors in patients with drug-resistant tuberculosis: A 7-year retrospective cohort study in Addis Ababa, Ethiopia
In this study involving patients with drug resistant tuberculosis, over half of the participants encountered at least one adverse drug reactions. Patient admission, baseline anemia, and older age were identified as major factors associated with adverse drug reaction during multidrug resistant tuberculosis treatment. Particular emphasis should be placed on these susceptible groups to facilitate early prediction, prompt management, and the formulation of appropriate treatment regimens that address adverse drug reactions effectively.
Authors
- Mbazi Senkoro
- Benjamin Solomon (ORCID: https://orcid.org/0000-0003-3059-5730)
- Tigest Ajeme
- Tsegahun Manyazewal (ORCID: https://orcid.org/0000-0002-8360-7574)
- Yimtubezinash Woldeamanuel
Institutions
- Addis Ababa University (ET)
Publication Details
- Journal
- Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1016/j.jctube.2025.100515
- Citations
- 2
- Primary Topic
- Pharmacovigilance and Adverse Drug Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- European Commission
- European and Developing Countries Clinical Trials Partnership