Adverse drug reactions and contributing factors in patients with drug-resistant tuberculosis: A 7-year retrospective cohort study in Addis Ababa, Ethiopia

In this study involving patients with drug resistant tuberculosis, over half of the participants encountered at least one adverse drug reactions. Patient admission, baseline anemia, and older age were identified as major factors associated with adverse drug reaction during multidrug resistant tuberculosis treatment. Particular emphasis should be placed on these susceptible groups to facilitate early prediction, prompt management, and the formulation of appropriate treatment regimens that address adverse drug reactions effectively.

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Publication Details

Journal
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Published
2025-03-05
DOI
https://doi.org/10.1016/j.jctube.2025.100515
Citations
2
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
2.61

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article

Adverse drug reactions and contributing factors in patients with drug-resistant tuberculosis: A 7-year retrospective cohort study in Addis Ababa, Ethiopia

Mbazi Senkoro, Benjamin Solomon, Tigest Ajeme, Tsegahun Manyazewal et al.
2 citations
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
Pharmacovigilance and Adverse Drug Reactions
2.61
article

Adverse drug reactions and contributing factors in patients with drug-resistant tuberculosis: A 7-year retrospective cohort study in Addis Ababa, Ethiopia

Mbazi Senkoro, Benjamin Solomon, Tigest Ajeme, Tsegahun Manyazewal, Yimtubezinash Woldeamanuel
article en
2 citations

Abstract

In this study involving patients with drug resistant tuberculosis, over half of the participants encountered at least one adverse drug reactions. Patient admission, baseline anemia, and older age were identified as major factors associated with adverse drug reaction during multidrug resistant tuberculosis treatment. Particular emphasis should be placed on these susceptible groups to facilitate early prediction, prompt management, and the formulation of appropriate treatment regimens that address adverse drug reactions effectively.

Journal of Clinical Tuberculosis and Other Mycobacterial DiseasesVol. 39
Addis Ababa University (ET)
European Commission, European and Developing Countries Clinical Trials Partnership
Good health and well-being
Openalex Percentile: Top 14%
Pharmacovigilance and Adverse Drug Reactions
2.61
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