Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study
Menopausal symptom burden is associated with poorer cognitive function and more MBI symptoms in mid- to late life. HT may help mitigate symptoms of MBI. These findings suggest that the experience of menopause may indicate susceptibility to cognitive and behavioural changes, both markers of dementia.
Authors
- Zahinoor Ismail (ORCID: https://orcid.org/0000-0002-5529-3731)
- Eric Edward Smith (ORCID: https://orcid.org/0000-0003-3956-1668)
- Dylan X. Guan (ORCID: https://orcid.org/0000-0002-7065-1963)
- Clive Ballard (ORCID: https://orcid.org/0000-0003-0022-5632)
- Adam Bloomfield (ORCID: https://orcid.org/0000-0002-5429-7378)
- Gillian Einstein (ORCID: https://orcid.org/0000-0002-0770-5471)
- Pamela Roach (ORCID: https://orcid.org/0000-0001-7694-9309)
- Anne Corbett (ORCID: https://orcid.org/0000-0003-2015-0316)
- Byron Creese (ORCID: https://orcid.org/0000-0001-6490-6037)
- Jasper F. E. Crockford
- Ellie Pickering
Institutions
- University of Calgary (CA)
- University of Toronto (CA)
- University of Exeter (GB)
- Baycrest Hospital (CA)
- Hotchkiss Brain Institute (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1371/journal.pone.0301165
- Citations
- 8
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 10.36