Outcomes after en bloc resection with sacrectomy of advanced colorectal carcinomas that invade the sacrum: a multiinstitutional descriptive series
En bloc resection is believed to offer the best local control in patients with locally invasive colorectal carcinoma. The present descriptive series highlights outcomes of en bloc resection with partial or full sacrectomy in patients with tumors showing local extension into the sacrum. Complications are common, most often in the form of wound dehiscence or infection, and many patients require placement in a rehabilitation or intermediate-care facility upon discharge. However, for those with stage III (locally aggressive) disease, median OS exceeds 16 years, suggesting that such aggressive management with en bloc resection may be warranted in properly selected patients.
Authors
- Chady Atallah (ORCID: https://orcid.org/0000-0002-0623-6271)
- Andrew M. Hersh (ORCID: https://orcid.org/0000-0003-1755-3974)
- Sheng-Fu Larry Lo (ORCID: https://orcid.org/0000-0001-7262-2544)
- Daniel M. Sciubba (ORCID: https://orcid.org/0000-0001-7604-434X)
- Zach Pennington (ORCID: https://orcid.org/0000-0001-8012-860X)
- Bashar Safar (ORCID: https://orcid.org/0000-0001-7712-9628)
- Aladine A. Elsamadicy (ORCID: https://orcid.org/0000-0002-7658-6461)
- Salem Najjar (ORCID: https://orcid.org/0000-0002-3813-806X)
- Gabrielle Santangelo (ORCID: https://orcid.org/0000-0001-6948-5147)
- Thomas Allyn Pieters (ORCID: https://orcid.org/0000-0001-8244-0787)
- Roee Ber (ORCID: https://orcid.org/0000-0003-3203-0717)
- Susan L. Gearhart (ORCID: https://orcid.org/0000-0002-0915-2188)
- Jean-Paul Wolinsky
- Bethany Hung (ORCID: https://orcid.org/0000-0003-0925-3533)
- Jonathan E. Efron
Institutions
- Northwestern University (US)
- Mayo Clinic (US)
- Hofstra University (US)
- Johns Hopkins University (US)
- University of Massachusetts Chan Medical School (US)
- Johns Hopkins Medicine (US)
- Yale University (US)
- Neurological Surgery (US)
- University of Rochester (US)
- New York University (US)
Publication Details
- Journal
- Journal of Neurosurgery Spine
- Published
- 2025-03-07
- DOI
- https://doi.org/10.3171/2024.10.spine24391
- Citations
- 1
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01