Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database
This comprehensive pharmacovigilance study not only confirmed previously known NCDIA associations but also identified new potential risk drugs. The novel risk classification system and detailed onset timing analysis provide valuable insights for clinical monitoring. The findings of earlier onset in specific populations and declining mortality trends have important implications for developing targeted surveillance strategies and improving patient safety management.
Authors
- Xiaojie Huang
- Shaokai Huang
- Xiaochun Xie
- Jiajia Chen (ORCID: https://orcid.org/0000-0002-6989-9048)
- Shanshan Wu (ORCID: https://orcid.org/0009-0002-7111-6804)
- Lina Huang
Institutions
- People 's Hospital of Jilin Province (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fphar.2025.1525307
- Citations
- 4
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- Medical Science and Technology Foundation of Guangdong Province