HPV integration profiling using nanopore sequencing and association with cervical precancerous lesion
A positive correlation exists between HPV integration frequency and cervical lesion stage. Late-stage lesions showed heightened enrichment in cancer-related pathways through specific HPV-integrated genes.
Authors
- Meina Bian
- Xiulan Li (ORCID: https://orcid.org/0000-0003-3524-637X)
- Yuxiang Zhou (ORCID: https://orcid.org/0000-0001-8653-2371)
- Huadong Tang (ORCID: https://orcid.org/0000-0002-9936-2444)
- Libin Zhang (ORCID: https://orcid.org/0000-0002-4611-1852)
- Weiwei Wang (ORCID: https://orcid.org/0000-0002-1886-6748)
- Xin Liu (ORCID: https://orcid.org/0000-0002-5319-1600)
- Xingyu Liu (ORCID: https://orcid.org/0009-0003-3815-4953)
- Yanmei Li (ORCID: https://orcid.org/0000-0003-1215-5010)
- Ying Hou (ORCID: https://orcid.org/0000-0002-5366-9934)
- Qing Liu (ORCID: https://orcid.org/0000-0001-6946-9120)
- Shoufeng Ni
- Jianyong Gao
- Nan Wang (ORCID: https://orcid.org/0000-0002-8842-3424)
- Fuqiang Xu (ORCID: https://orcid.org/0000-0002-4382-9797)
Institutions
- Capital Medical University (CN)
- Cipher Gene (China) (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fmicb.2025.1522550
- Citations
- 1
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81