A study of the safety and efficacy of multi-mode NMR-guided double-antiplatelet pretreatment combined with low-dose rtPA in the treatment of acute mild ischemic stroke
After dual antiplatelet pretreatment combined with low-dose rtPA intravenous thrombolysis for acute mild stroke under multimodal MRI guidance, the proportion of patients with good functional outcomes within 90 days was higher compared to the DAPT group and the standard-dose group, with statistical significance. There was no significant increase in the risk of cerebral hemorrhage compared to the standard-dose group and the DAPT group.
Authors
- Xia Li (ORCID: https://orcid.org/0000-0002-5178-8059)
- Peilan Zhang (ORCID: https://orcid.org/0000-0002-6054-4494)
- Yan Chen (ORCID: https://orcid.org/0000-0002-8028-1679)
- Ping Chen (ORCID: https://orcid.org/0000-0002-9805-2022)
- Fangfang Zhang (ORCID: https://orcid.org/0000-0002-6161-022X)
- Zhong Dong (ORCID: https://orcid.org/0000-0001-9970-6510)
Institutions
- Tianjin Huanhu Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fneur.2025.1482078
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00