A study of the safety and efficacy of multi-mode NMR-guided double-antiplatelet pretreatment combined with low-dose rtPA in the treatment of acute mild ischemic stroke

After dual antiplatelet pretreatment combined with low-dose rtPA intravenous thrombolysis for acute mild stroke under multimodal MRI guidance, the proportion of patients with good functional outcomes within 90 days was higher compared to the DAPT group and the standard-dose group, with statistical significance. There was no significant increase in the risk of cerebral hemorrhage compared to the standard-dose group and the DAPT group.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-03-05
DOI
https://doi.org/10.3389/fneur.2025.1482078
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
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article

A study of the safety and efficacy of multi-mode NMR-guided double-antiplatelet pretreatment combined with low-dose rtPA in the treatment of acute mild ischemic stroke

Xia Li, Peilan Zhang, Yan Chen, Ping Chen et al.
Frontiers in Neurology
Acute Ischemic Stroke Management
article

A study of the safety and efficacy of multi-mode NMR-guided double-antiplatelet pretreatment combined with low-dose rtPA in the treatment of acute mild ischemic stroke

Xia Li, Peilan Zhang, Yan Chen, Ping Chen, Fangfang Zhang, Zhong Dong
article en

Abstract

After dual antiplatelet pretreatment combined with low-dose rtPA intravenous thrombolysis for acute mild stroke under multimodal MRI guidance, the proportion of patients with good functional outcomes within 90 days was higher compared to the DAPT group and the standard-dose group, with statistical significance. There was no significant increase in the risk of cerebral hemorrhage compared to the standard-dose group and the DAPT group.

Frontiers in NeurologyVol. 16
Tianjin Huanhu Hospital (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 94%
Acute Ischemic Stroke Management
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A study of the safety and efficacy of multi-mode NMR-guided double-antiplatelet pretreatment combined with low-dose rtPA in the treatment of acute mild ischemic stroke — Xia Li, Peilan Zhang, et al. · Frontiers in Neurology (2025) | TGRS Research Map | TGRS