Determining safe washout period for immune checkpoint inhibitors prior to liver transplantation: An international retrospective cohort study
Our findings suggest that a washout period longer than 50 days for ICIs before LT appears to be safe with respect to rejection risk. While these results may help guide clinical decision-making, future prospective studies are essential to establish definitive guidelines.
Authors
- Anand Kulkarni (ORCID: https://orcid.org/0000-0002-2983-0548)
- Sofia El Hajji (ORCID: https://orcid.org/0000-0002-3028-6148)
- Mercedes Martínez (ORCID: https://orcid.org/0000-0001-6128-0155)
- Pramod Kumar (ORCID: https://orcid.org/0000-0002-1073-6295)
- Miguel Sogbe (ORCID: https://orcid.org/0000-0002-2846-7812)
- Philippe Compagnon (ORCID: https://orcid.org/0000-0002-7423-5887)
- Robyn D. Gartrell (ORCID: https://orcid.org/0000-0003-3287-4223)
- Parissa Tabrizian (ORCID: https://orcid.org/0000-0002-7881-7497)
- Yasmina Chouik (ORCID: https://orcid.org/0000-0001-7548-3703)
- Elise Kang (ORCID: https://orcid.org/0000-0002-4189-6697)
- Gabriel T. Schnickel (ORCID: https://orcid.org/0000-0003-4392-2200)
- Stéphanie Lacotte (ORCID: https://orcid.org/0000-0002-5921-6389)
- Glenda Meeberg
- Constantine Jason Karvellas (ORCID: https://orcid.org/0000-0002-1555-1089)
- Birgit Schwacha-Eipper
- Christian Toso (ORCID: https://orcid.org/0000-0003-1652-4522)
- Beat Moeckli (ORCID: https://orcid.org/0000-0002-9020-8416)
- Andreas Schmiderer (ORCID: https://orcid.org/0000-0003-3496-2657)
- Nicolas Goossens (ORCID: https://orcid.org/0000-0002-8698-4690)
- Bruno Sangro (ORCID: https://orcid.org/0000-0002-4177-6417)
- Charles‐Henri Wassmer (ORCID: https://orcid.org/0000-0002-9018-7088)
- Joana Rodrigues Ribeiro
- Rohan Kumar (ORCID: https://orcid.org/0000-0003-4477-211X)
- Sonal Asthana
- Manon Allaire (ORCID: https://orcid.org/0000-0001-8199-1501)
- Hao Feng (ORCID: https://orcid.org/0000-0002-0794-8422)
- Lai Wei (ORCID: https://orcid.org/0009-0008-6761-3158)
Institutions
- University of Geneva (CH)
- Mount Sinai Hospital (US)
- Innsbruck Medical University (AT)
- Johns Hopkins University (US)
- University of Alberta (CA)
- Universität Innsbruck (AT)
- Université Paris Cité (FR)
- Columbia University Irving Medical Center (US)
- Johns Hopkins Medicine (US)
- Renji Hospital (CN)
- University Hospital of Bern (CH)
- Gleneagles Hospital (SG)
- University of California San Diego (US)
- Sorbonne Université (FR)
- Hôpital de la Croix-Rousse (FR)
- Mount Sinai Medical Center (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Global Hospitals (IN)
- Centro de Investigación Biomédica en Red (ES)
- Clinica Universidad de Navarra (ES)
- BGS Global Hospital (IN)
- Tongji Hospital (CN)
- Columbia University (US)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Hepatology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1097/hep.0000000000001289
- Citations
- 29
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 57.57