Evaluation of in vitro pharmacological activities of medicinal mushrooms in the context of dry eye disease
Several extracts of the investigated fungal materials exhibit multifaceted pharmacological <i>in vitro</i> activities. Due to low cytotoxic activity on HCE-T, iHMGEC, and THP-1 cells, extracts from GL and GO are particularly pertinent to the treatment of DED, even at low concentrations.
Authors
- Carsten Gründemann (ORCID: https://orcid.org/0000-0003-0240-0342)
- Andreas Wasilewicz (ORCID: https://orcid.org/0000-0003-3396-5071)
- Sven Nicolay (ORCID: https://orcid.org/0009-0006-7924-3364)
- Amy Marisa Zimmermann-Klemd
- Judith M. Rollinger (ORCID: https://orcid.org/0000-0001-6581-0774)
- Ulrike Grienke (ORCID: https://orcid.org/0000-0003-0305-9270)
- Alexander Areesanan
Institutions
- University of Vienna (AT)
- University of Basel (CH)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fphar.2025.1557359
- Citations
- 3
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 5.64