83P A single-arm meta-analysis of the safety and efficacy of erdafitinib in patients with FGFR-altered urothelial carcinoma and solid tumors previously treated with systemic therapy

Erdafitinib is a pan-FGFR inhibitor approved for treating locally advanced or metastatic urothelial carcinoma and solid tumors with FGFR alterations after previous systemic therapy. We aim to evaluate its safety and efficacy in patients with FGFR-altered solid tumors, including urothelial carcinoma.

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Publication Details

Journal
ESMO Open
Published
2025-03-01
DOI
https://doi.org/10.1016/j.esmoop.2025.104242
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

83P A single-arm meta-analysis of the safety and efficacy of erdafitinib in patients with FGFR-altered urothelial carcinoma and solid tumors previously treated with systemic therapy

Mahmoud Elsawy, Amr Ehab El‐Qushayri, Mohamed Arafa, Ahmad R. Al‐Qudimat et al.
ESMO Open
Bladder and Urothelial Cancer Treatments
article

83P A single-arm meta-analysis of the safety and efficacy of erdafitinib in patients with FGFR-altered urothelial carcinoma and solid tumors previously treated with systemic therapy

Mahmoud Elsawy, Amr Ehab El‐Qushayri, Mohamed Arafa, Ahmad R. Al‐Qudimat, Muhamad Amin Rifai, Ahmed Ibrahim Ahmed, Laila Shalabi, M. Asif, Sofian Zreigh, Ahmed Al Sakini, Yaqeen Alsheyab
article en

Abstract

Erdafitinib is a pan-FGFR inhibitor approved for treating locally advanced or metastatic urothelial carcinoma and solid tumors with FGFR alterations after previous systemic therapy. We aim to evaluate its safety and efficacy in patients with FGFR-altered solid tumors, including urothelial carcinoma.

ESMO OpenVol. 10
University of Jordan (JO), Alfaisal University (SA), University of Baghdad (IQ), Al-Azhar University (EG), Hamad General Hospital (QA), Ankara Yıldırım Beyazıt University (TR), Shebin Teaching Hospital (EG), Hamad Medical Corporation (QA), Alexandria University (EG), Minia University (EG)
Good health and well-being
Openalex Percentile: Top 93%
Bladder and Urothelial Cancer Treatments
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