Population Pharmacokinetic-Pharmacodynamic (popPK/PD) Relationship of Orismilast, A Potent and Selective PDE4B/D Inhibitor, in Atopic Dermatitis
The outcome of the analysis supports the observed clinical effect of orismilast in patients with AD and could explain the lack of efficacy of apremilast in the same indication.
Authors
- Anne Weiss (ORCID: https://orcid.org/0000-0002-1738-0519)
- Morten Otto Alexander Sommer (ORCID: https://orcid.org/0000-0003-4005-5674)
- Jakob Felding
- Richard Bruce Warren (ORCID: https://orcid.org/0000-0002-2918-6481)
Institutions
- Salford Royal NHS Foundation Trust (GB)
- Novo Nordisk Foundation (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Dermatology and Therapy
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1007/s13555-025-01371-9
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00