Analysis of the relationship between sugar intake and cancer prevalence: a cross-sectional study using the 8th Korea National Health and Nutrition Examination Survey

Objectives: This study aimed to analyze the association between sugar intake and cancer risk among Korean adults aged 19 years and older.Methods: A total of 13,016 adults aged 19 years and older who participated in the 8th Korea National Health and Nutrition Examination Survey from 2019 to 2021 were included. Sugar intake was assessed in terms of both absolute intake and sugar energy rate. Sugar intake was divided into quartiles, while sugar energy rate was categorized into three groups (< 10%, 10%–20%, > 20%) based on the 2020 Dietary Reference Intakes for Koreans and into two groups (< 10%, ≥ 10%) based on WHO recommendations. Cancer prevalence was determined using cancer-related survey questions. The association between sugar intake and cancer prevalence was analyzed by sex and cancer type using logistic regression. All statistical analyses were performed using IBM SPSS statistics 29.0 (IBM Co.). Results: From 2019 to 2021, sugar intake significantly declined with age in both men and women (P for trend < 0.001), with the highest intake observed in the 19–29 age group (61.38 g). Men consumed significantly more sugar than women across all age groups except for the 50–64 and 65–74 groups (P < 0.05). However, the sugar energy rate was significantly higher in women than in men (P < 0.05). While the association between sugar intake and cancer prevalence varied across regression models and cancer types, cervical cancer consistently showed a significant association with sugar intake (P < 0.05). Conclusion: The association between sugar energy rate and the prevalence of premenopausal cervical cancer was consistent and significant. Given that women had a higher sugar energy rate than men, the relationship between sugar intake and cancer prevalence in women warrants further investigation. Longitudinal studies with more detailed sugar intake assessments are needed.