Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway
These results demonstrate that srebf2 and the downstream mevalonate synthesis pathway plays an important role in regulating efficient axon regeneration in the zebrafish visual system. Involvement of this pathway should be closely examined in failed mammalian ON regeneration.
Authors
- Matthew B. Veldman (ORCID: https://orcid.org/0000-0002-0328-5916)
- Meng-Ming Hu (ORCID: https://orcid.org/0000-0003-0791-5740)
Institutions
- Medical College of Wisconsin (US)
Publication Details
- Journal
- Molecular Neurodegeneration
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1186/s13024-025-00807-2
- Citations
- 3
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Institute of Neurological Disorders and Stroke