Physical Activity, Alzheimer Plasma Biomarkers, and Cognition
These findings suggest that PA may help delay cognitive decline by modulating neurodegeneration and AD-specific tau pathologies. However, the cross-sectional design limits causal inference, and longitudinal studies are needed to confirm and clarify these associations.
Authors
- Sang‐Hyuk Jung (ORCID: https://orcid.org/0000-0003-4116-3327)
- Seunghee Na (ORCID: https://orcid.org/0000-0001-8578-8578)
- Yeshin Kim (ORCID: https://orcid.org/0000-0002-4643-5478)
- Young Noh (ORCID: https://orcid.org/0000-0002-9633-3314)
- Jin‐Kyu Seo
- Byeong C. Kim (ORCID: https://orcid.org/0000-0001-6827-6730)
- Na Kyung Lee (ORCID: https://orcid.org/0000-0001-6116-2562)
- Yuna Gu (ORCID: https://orcid.org/0009-0007-3200-3977)
- Yeongshin Kim (ORCID: https://orcid.org/0009-0008-4925-194X)
- Jee Hyang Jeong (ORCID: https://orcid.org/0000-0001-7945-6956)
- Ki Young Shin (ORCID: https://orcid.org/0000-0002-9847-1032)
- Jong Hun Kim (ORCID: https://orcid.org/0000-0003-3830-650X)
- Bo Kyoung Cheon (ORCID: https://orcid.org/0000-0002-5613-517X)
- Duk Lyul Na (ORCID: https://orcid.org/0000-0002-0098-7592)
- Na‐Yeon Jung (ORCID: https://orcid.org/0000-0002-8265-9508)
- Seung Ae Kim (ORCID: https://orcid.org/0000-0001-5197-7442)
- Yejoo Choi
- So Young Moon (ORCID: https://orcid.org/0000-0002-1025-1968)
- Minyoung Cho (ORCID: https://orcid.org/0000-0001-5023-0902)
- Yu Hyun Park (ORCID: https://orcid.org/0000-0002-3248-9993)
- Hong-Hee Won
- Soo-Jong Kim
- Ko Woon Kim (ORCID: https://orcid.org/0000-0002-4564-9714)
- Jae‐Won Jang (ORCID: https://orcid.org/0000-0003-3540-530X)
- Jin San Lee (ORCID: https://orcid.org/0000-0002-5017-854X)
- Geon Ha Kim (ORCID: https://orcid.org/0000-0001-5395-1924)
- Hongki Ham (ORCID: https://orcid.org/0009-0002-0806-6453)
- Hyemin Jang (ORCID: https://orcid.org/0000-0003-3152-1274)
- Eek‐Sung Lee (ORCID: https://orcid.org/0000-0003-3517-8207)
- Do Kyung Lee (ORCID: https://orcid.org/0000-0001-6596-1222)
- Dahyun Yi (ORCID: https://orcid.org/0000-0002-0860-0946)
- Byung-Hyun Byun
- Kaj Blennow
- Gang Seob Jung (ORCID: https://orcid.org/0000-0002-8047-6505)
- Sung Hoon Kang (ORCID: https://orcid.org/0000-0002-2481-0302)
- Young Hee Jung (ORCID: https://orcid.org/0000-0002-8945-2200)
- Ji Sung Jang (ORCID: https://orcid.org/0000-0001-9300-3945)
- Chi‐Hun Kim (ORCID: https://orcid.org/0000-0001-8167-4530)
- Young‐Ju Kim
- Han Jo Kim (ORCID: https://orcid.org/0000-0001-7880-690X)
- Young-Soo Kim (ORCID: https://orcid.org/0000-0002-7991-7983)
- Dong Hyun Lee
- Hanna Cho (ORCID: https://orcid.org/0000-0001-5936-1546)
- Junkyu Choi
- Seung Joo Kim (ORCID: https://orcid.org/0000-0001-9391-1767)
- Han Na Lee
- Beomsu Kim (ORCID: https://orcid.org/0000-0002-5656-7191)
- Soo Hyun Cho (ORCID: https://orcid.org/0000-0002-4262-1468)
- Sang Won Seo (ORCID: https://orcid.org/0000-0003-2568-0797)
- Daeun Shin (ORCID: https://orcid.org/0000-0003-4834-1026)
- Kyunghun Kang (ORCID: https://orcid.org/0000-0003-2221-8046)
- Si Eun Kim
- Yeo Jin Kim
- Juhee Chin
- Hang-Rai Kim
- Y. Ha
- C. H. YOON
- S. H. Eom
- Min Soo Byun
- Sang Won Seo (ORCID: https://orcid.org/0000-0002-4262-1468)
- H. X. Yang (ORCID: https://orcid.org/0009-0007-1308-4724)
- Henrik Zetterberg (ORCID: https://orcid.org/0000-0002-4671-6763)
- Sun-Ho Han
- Hae-Eun Shin
- Joon-Kyung Seong
- Dong Young Lee (ORCID: https://orcid.org/0009-0006-0924-6607)
- Haesook Bok
Institutions
- University of Science and Technology of China (CN)
- Seoul National University (KR)
- Kangwon National University (KR)
- Sahlgrenska University Hospital (SE)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Sorbonne Université (FR)
- Evidence Based Research (United States) (US)
- Pitié-Salpêtrière Hospital (FR)
- Dr Youth Clinic (KR)
- UK Dementia Research Institute (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Institut du Cerveau (FR)
- University College London (GB)
- Sungkyunkwan University (KR)
- University of Gothenburg (SE)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.0096
- Citations
- 16
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 23.54