Left portal vein thrombosis as an unusual complication following acute cholecystitis: case report and literature review

Portal vein thrombosis (PVT) is a rare but potentially severe condition that is typically associated with underlying haematological disorders, genetic mutations, or liver diseases such as cirrhosis. However, PVT resulting from acute cholecystitis is an exceedingly uncommon occurrence with few documented cases. This report describes the case of a 44-year-old man who presented with acute right upper quadrant pain and was diagnosed with acute cholecystitis complicated by left-sided PVT, which was managed with anticoagulants and laparoscopic cholecystectomy. This case underscores the complexity of managing acute cholecystitis complicated by PVT. Although anticoagulation remains the cornerstone of PVT management, concurrent surgical intervention for cholecystitis poses challenges in terms of timing and perioperative care. A multidisciplinary approach tailored to the individual patient is crucial to achieving optimal outcomes.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-03-01
DOI
https://doi.org/10.1093/jscr/rjaf118
Citations
2
Primary Topic
Gallbladder and Bile Duct Disorders
Type
article
Field-Weighted Citation Impact
3.04
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article

Left portal vein thrombosis as an unusual complication following acute cholecystitis: case report and literature review

Faisal A Almudaiheem, Bandar Ali, Mohammed Al-Jabali, Majed Alanazi
2 citations
Journal of Surgical Case Reports
Gallbladder and Bile Duct Disorders
3.04
article

Left portal vein thrombosis as an unusual complication following acute cholecystitis: case report and literature review

Faisal A Almudaiheem, Bandar Ali, Mohammed Al-Jabali, Majed Alanazi
article en
2 citations

Abstract

Portal vein thrombosis (PVT) is a rare but potentially severe condition that is typically associated with underlying haematological disorders, genetic mutations, or liver diseases such as cirrhosis. However, PVT resulting from acute cholecystitis is an exceedingly uncommon occurrence with few documented cases. This report describes the case of a 44-year-old man who presented with acute right upper quadrant pain and was diagnosed with acute cholecystitis complicated by left-sided PVT, which was managed with anticoagulants and laparoscopic cholecystectomy. This case underscores the complexity of managing acute cholecystitis complicated by PVT. Although anticoagulation remains the cornerstone of PVT management, concurrent surgical intervention for cholecystitis poses challenges in terms of timing and perioperative care. A multidisciplinary approach tailored to the individual patient is crucial to achieving optimal outcomes.

Journal of Surgical Case ReportsVol. 2025(3)
Riyadh Armed Forces Hospital (SA)
Openalex Percentile: Top 11%
Gallbladder and Bile Duct Disorders
3.04
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Left portal vein thrombosis as an unusual complication following acute cholecystitis: case report and literature review — Faisal A Almudaiheem, Bandar Ali, et al. · Journal of Surgical Case Reports (2025) | TGRS Research Map | TGRS