A Rare Case of Concurrent Primary Biliary Cholangitis and Sarcoidosis

Primary biliary cholangitis and sarcoidosis are the two most common causes of granulomatous liver disease in the US; however, their expected clinical course and management are starkly different. This case involves a patient with granulomas noted on liver biopsy, presumed secondary to known sarcoidosis, later found to have concurrent primary biliary cholangitis. Prompt diagnosis of primary biliary cholangitis is crucial as its natural course of progressive liver fibrosis can be significantly improved with treatment.

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Publication Details

Journal
Cureus
Published
2025-03-07
DOI
https://doi.org/10.7759/cureus.80228
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Concurrent Primary Biliary Cholangitis and Sarcoidosis

Laxmikausthubha Yaratha, Mamoun Younes, Marie L. Borum, Mrudula Bandaru et al.
Cureus
Liver Diseases and Immunity
article

A Rare Case of Concurrent Primary Biliary Cholangitis and Sarcoidosis

Laxmikausthubha Yaratha, Mamoun Younes, Marie L. Borum, Mrudula Bandaru, Robert S. Gordon
article en

Abstract

Primary biliary cholangitis and sarcoidosis are the two most common causes of granulomatous liver disease in the US; however, their expected clinical course and management are starkly different. This case involves a patient with granulomas noted on liver biopsy, presumed secondary to known sarcoidosis, later found to have concurrent primary biliary cholangitis. Prompt diagnosis of primary biliary cholangitis is crucial as its natural course of progressive liver fibrosis can be significantly improved with treatment.

CureusVol. 17(3)
George Washington University (US)
Zero hunger
Openalex Percentile: Top 94%
Liver Diseases and Immunity
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