Effectiveness and Safety of Upadacitinib Induction Therapy for 223 Patients With Crohn's Disease: A <scp>GETAID</scp> Multicentre Cohort Study

In this real-world cohort of highly refractory CD patients, upadacitinib induction resulted in a clinical response in about two-thirds of patients and in SFCR in half of the patients, with an acceptable safety profile.

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Publication Details

Journal
Alimentary Pharmacology & Therapeutics
Published
2025-03-04
DOI
https://doi.org/10.1111/apt.70073
Citations
8
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
14.54
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article

Effectiveness and Safety of Upadacitinib Induction Therapy for 223 Patients With Crohn's Disease: A GETAID Multicentre Cohort Study

Stéphane Nancey, David Laharie, Philippe Marteau, Ludovic Caillo et al.
8 citations
Alimentary Pharmacology & Therapeutics
Inflammatory Bowel Disease
14.54
article

Effectiveness and Safety of Upadacitinib Induction Therapy for 223 Patients With Crohn's Disease: A GETAID Multicentre Cohort Study

Stéphane Nancey, David Laharie, Philippe Marteau, Ludovic Caillo, Aurélien Amiot, Laurent Peyrin‐Biroulet, Matthieu Allez, Benoît Coffin, Guillaume Bouguen, Mathurin Fuméry, Anthony Buisson, Lucine Vuitton, Cyrielle Gilletta, Romain Altwegg, Nicolas Richard, Maria Nachury, Catherine Le Berre, Mathieu Uzzan, Cléa Rouilon
article en
8 citations

Abstract

In this real-world cohort of highly refractory CD patients, upadacitinib induction resulted in a clinical response in about two-thirds of patients and in SFCR in half of the patients, with an acceptable safety profile.

Alimentary Pharmacology & TherapeuticsVol. 61(10)
Université Claude Bernard Lyon 1 (FR), Université de Bordeaux (FR), Inserm (FR), Université Paris-Est Créteil (FR), Université Clermont Auvergne (FR), Université Paris Cité (FR), Université de Lille (FR), Université Paris-Saclay (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Lille (FR), Sorbonne Université (FR), Hôpital Louis-Mourier (FR), Centre Hospitalier Universitaire de Montpellier (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Hôpital Saint-Antoine (FR), Centre de recherche en Epidémiologie et Santé des Populations (FR), Fédération Hospitalo-Universitaire, Paris Center for Microbiome Medicine (FR), CIC Rennes (FR), Hôpital Cardiologique du Haut-Lévêque (FR), Hôpital Rangueil (FR), Microbe, Intestine, Inflammation and Host Susceptibility (FR), Lille Inflammation Research International Center (FR), Hôpital Saint-Louis (FR), Hôpital Bichat-Claude-Bernard (FR), Centre Hospitalier Universitaire de Rennes (FR), Périnatalité & Risques Toxiques (FR), Centre International de Recherche en Infectiologie (FR), Bicêtre Hospital (FR), Institute for Translational Research in Inflammation (FR), Nutrition-Génétique et Exposition aux Risques Environnementaux (FR), Nutrition, métabolismes et cancer (FR), Université de Rennes (FR), Université de Rouen Normandie (FR), Université de Lorraine (FR), Université de Franche-Comté (FR), Nantes Université (FR), Université de Caen Normandie (FR)
Good health and well-being
Openalex Percentile: Top 1%
Inflammatory Bowel Disease
14.54
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