Treatment Approach for Metastatic Intracranial Germinoma: A Multi‐Institutional Experience

Our data show that pre-irradiation induction chemotherapy followed by CSI is associated with excellent overall survival in patients with metastatic germinoma. Importantly, our experience suggests that in combination with induction chemotherapy, 21 Gy CSI may be sufficient as a curative dose in this patient population.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-03-04
DOI
https://doi.org/10.1002/pbc.31628
Citations
1
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.63
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article

Treatment Approach for Metastatic Intracranial Germinoma: A Multi‐Institutional Experience

David H. Ebb, Torunn Ingrid Yock, Kevin X. Liu, Karen Jean Marcus et al.
1 citations
Pediatric Blood & Cancer
Glioma Diagnosis and Treatment
1.63
article

Treatment Approach for Metastatic Intracranial Germinoma: A Multi‐Institutional Experience

David H. Ebb, Torunn Ingrid Yock, Kevin X. Liu, Karen Jean Marcus, Shannon M. MacDonald, Kee Kiat Yeo, Susan Chi, Myrsini Ioakeim‐Ioannidou, Daphne Adele Haas-Kogan, Karen D. Wright, Phoebe C. Power, Hesham Elhalawani, Roshan V. Sethi
article en
1 citations

Abstract

Our data show that pre-irradiation induction chemotherapy followed by CSI is associated with excellent overall survival in patients with metastatic germinoma. Importantly, our experience suggests that in combination with induction chemotherapy, 21 Gy CSI may be sufficient as a curative dose in this patient population.

Pediatric Blood & CancerVol. 72(5)
Brigham and Women's Hospital (US), Massachusetts General Hospital (US), Dana-Farber Brigham Cancer Center (US), Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
Openalex Percentile: Top 20%
Glioma Diagnosis and Treatment
1.63
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