Germline Genetic Testing in Breast Cancer: Utilization and Disparities in a Middle-Income Country
Only 9% of this robust Brazilian BC cohort underwent GGT, highlighting a considerable gap from the current recommendation to test all patients with BC under age 65 years. GGT is underused by patients with HR in both public and private health care systems, with those in the public system being more affected. The disparities and barriers identified emphasize the need for educational interventions and enhanced access to GGT. Prioritizing GGT is critical to improving BC outcomes in LMICs.
Authors
- Vladmir Cláudio Cordeiro de Lima (ORCID: https://orcid.org/0000-0003-3955-1101)
- Giovana Zerwes Vacaro
- Susanne Crocamo (ORCID: https://orcid.org/0000-0002-5463-5517)
- Brigitte Van Eyll
- Rita de Cássia Costamilan
- José Bines (ORCID: https://orcid.org/0000-0003-2465-8854)
- Rafaela Gomes de Jesus (ORCID: https://orcid.org/0000-0001-6912-2995)
- Ruffo Freitas‐Júnior (ORCID: https://orcid.org/0000-0003-4145-8598)
- José Varela Donato Filho (ORCID: https://orcid.org/0009-0001-4010-9997)
- Nicolas Lazaretti
- Eduardo Cronemberger (ORCID: https://orcid.org/0000-0001-8493-7287)
- Diocésio Alves Pinto de Andrade (ORCID: https://orcid.org/0000-0003-2715-2197)
- Karla Emerenciano
- Heloísa Resende (ORCID: https://orcid.org/0000-0003-4692-3743)
- Juliana Giacomazzi (ORCID: https://orcid.org/0000-0001-5811-5140)
- Max S. Mano (ORCID: https://orcid.org/0000-0001-5666-5261)
- André P. Fay (ORCID: https://orcid.org/0000-0002-8588-7012)
- Alessandra Morelle (ORCID: https://orcid.org/0000-0002-0744-4523)
- Tomás Reinert (ORCID: https://orcid.org/0000-0003-4715-1415)
- Vanessa Dybal (ORCID: https://orcid.org/0000-0001-8779-5923)
- Gustavo Werutsky (ORCID: https://orcid.org/0000-0001-6271-105X)
- Alessandra Borba Anton de Souza (ORCID: https://orcid.org/0000-0002-6215-7076)
- Martina Lichtenfels (ORCID: https://orcid.org/0000-0003-4783-4646)
- Carlos H. Barrios (ORCID: https://orcid.org/0000-0001-6021-667X)
- Carlos Sampaio (ORCID: https://orcid.org/0000-0002-9786-2306)
- Giuliano Santos Borges
- Clarissa Mathias (ORCID: https://orcid.org/0000-0002-6219-9858)
- Geraldo Silva Queiroz
- Sérgio D. Simon (ORCID: https://orcid.org/0000-0003-3278-4762)
- Daniela D. Rosa
- Yeni Nerón
Institutions
- AC Camargo Hospital (BR)
- Universidade de Caxias do Sul (BR)
- Hospital Moinhos de Vento (BR)
- Instituto do Câncer do Estado de São Paulo (BR)
- Hospital Ortopédico de Passo Fundo (BR)
- Faculdade da Serra Gaúcha (BR)
- Hospital Araújo Jorge (BR)
- Hospital São Vicente (BR)
- Instituto Nacional de Câncer - INCA (BR)
- Clinics Hospital of Ribeirão Preto (BR)
- Centro de Pesquisas Oncológicas (BR)
- Pontifícia Universidade Católica do Rio Grande do Sul (BR)
- Fundação Oswaldo Cruz (BR)
- Universidade Federal de Goiás (BR)
Publication Details
- Journal
- JCO Global Oncology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1200/go-24-00337
- Citations
- 1
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.82