Phase II Evaluation of Ultra-Hypofractionated Postoperative Radiation Therapy for Breast Cancer: Toxicity and Efficacy in a Single-Center Nonrandomized Prospective Study

This study demonstrates the safety of ultra-hypofractionated radiation therapy in terms of toxicity in patients with breast cancer. The findings for side effects, cosmesis, quality of life, and survival outcomes are consistent with those observed in moderately hypofractionated radiation therapy regimens, suggesting its use as a viable treatment option in this demographic.

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Publication Details

Journal
JCO Global Oncology
Published
2025-03-01
DOI
https://doi.org/10.1200/go-24-00277
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Phase II Evaluation of Ultra-Hypofractionated Postoperative Radiation Therapy for Breast Cancer: Toxicity and Efficacy in a Single-Center Nonrandomized Prospective Study

Rossana Veronica Mendoza López, Lucas Coelho Casimiro, Gabriele Pinto, Vinícius de Carvalho Gico et al.
JCO Global Oncology
Breast Cancer Treatment Studies
article

Phase II Evaluation of Ultra-Hypofractionated Postoperative Radiation Therapy for Breast Cancer: Toxicity and Efficacy in a Single-Center Nonrandomized Prospective Study

Rossana Veronica Mendoza López, Lucas Coelho Casimiro, Gabriele Pinto, Vinícius de Carvalho Gico, Marcel Fang, Elson Santos Neto, Gustavo Nader Marta, Bruno Takatsu
article en

Abstract

This study demonstrates the safety of ultra-hypofractionated radiation therapy in terms of toxicity in patients with breast cancer. The findings for side effects, cosmesis, quality of life, and survival outcomes are consistent with those observed in moderately hypofractionated radiation therapy regimens, suggesting its use as a viable treatment option in this demographic.

JCO Global OncologyVol. 11(11)
Universidade de São Paulo (BR), Hebrew University of Jerusalem (IL), Hadassah Medical Center (IL), AC Camargo Hospital (BR), Instituto do Câncer do Estado de São Paulo (BR), Faculdade de Ciências Médicas da Santa Casa de São Paulo (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR), Hospital Sírio-Libanês (BR)
Good health and well-being
Openalex Percentile: Top 95%
Breast Cancer Treatment Studies
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Phase II Evaluation of Ultra-Hypofractionated Postoperative Radiation Therapy for Breast Cancer: Toxicity and Efficacy in a Single-Center Nonrandomized Prospective Study — Rossana Veronica Mendoza López, Lucas Coelho Casimiro, et al. · JCO Global Oncology (2025) | TGRS Research Map | TGRS