Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71
An undescribed fusaric acid derivative, fusaricate L (<b>1</b>) was isolated together with eight known compounds (<b>2</b>-<b>9</b>) from mangrove plant <i>Rhizophora apiculata</i> rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds <b>4</b>, <b>6</b>, <b>7</b> and <b>9</b> showed modest antimicrobial activities towards methicillin- susceptible <i>Staphylococcus aureus</i>.
Authors
- Jing-Jing Ye
- Zhenyi Liang
- Ruibin Kuang
- Jiajia Lu (ORCID: https://orcid.org/0009-0003-7926-8834)
- Jing Xu (ORCID: https://orcid.org/0000-0002-6201-5318)
Institutions
- Qingdao University (CN)
- Hainan University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1080/14786419.2025.2475510
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China