Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71

An undescribed fusaric acid derivative, fusaricate L (<b>1</b>) was isolated together with eight known compounds (<b>2</b>-<b>9</b>) from mangrove plant <i>Rhizophora apiculata</i> rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds <b>4</b>, <b>6</b>, <b>7</b> and <b>9</b> showed modest antimicrobial activities towards methicillin- susceptible <i>Staphylococcus aureus</i>.

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Publication Details

Journal
Natural Product Research
Published
2025-03-07
DOI
https://doi.org/10.1080/14786419.2025.2475510
Primary Topic
Fungal Biology and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived Streptomyces angustmyceticus J-71

Jing-Jing Ye, Zhenyi Liang, Ruibin Kuang, Jiajia Lu et al.
Natural Product Research
Fungal Biology and Applications
article

Fusaricate L, a new fusaric acid derivative from mangrove rhizosphere soil-derived Streptomyces angustmyceticus J-71

Jing-Jing Ye, Zhenyi Liang, Ruibin Kuang, Jiajia Lu, Jing Xu
article en

Abstract

An undescribed fusaric acid derivative, fusaricate L (<b>1</b>) was isolated together with eight known compounds (<b>2</b>-<b>9</b>) from mangrove plant <i>Rhizophora apiculata</i> rhizosphere soil-derived <i>Streptomyces angustmyceticus</i> J-71. The structures of these compounds were established by extensive NMR spectroscopic data and comparison with the data of literature. Moreover, all isolated metabolites were tested for antifungal and antibacterial activities against a panel of plant and human pathogens. Compounds <b>4</b>, <b>6</b>, <b>7</b> and <b>9</b> showed modest antimicrobial activities towards methicillin- susceptible <i>Staphylococcus aureus</i>.

Natural Product Research
Qingdao University (CN), Hainan University (CN), Affiliated Hospital of Qingdao University (CN)
National Natural Science Foundation of China
Life in Land
Openalex Percentile: Top 95%
Fungal Biology and Applications
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