A Randomized controlled clinical study to evaluate the wound healing activity of Durvadi Ghrita in Clean wounds w.s.r to Shuddha Vrana

Introduction: The wound which is referred as Vrana is the oldest ailment from which the humankind has suffered. Man has made every effort to deal with the problems caused by trauma since the dawn of civilization. A thorough analysis of the Ayurvedic classics revealed that Durva is one of the medications with wound-healing capabilities. Objective: To evaluate the wound healing activity of Durvadi Ghrita in Clean wounds. Methodology: A single blind clinical study with pre-test and post-test design. The 30 patients with diagnostic criteria of Shuddha Vrana were selected from R.G.G.P.G. Ayurvedic College, Paprola, District Kangra, Himachal Pradesh. In Group A, the wound is dressed with Povidone Iodine. In the group B, Durvadi Ghrita was used for dressing. Wound management done once in a day. Duration of the study was 28 days. Follow up done once in 7 days for 1 month. The data were graded based on the assessment criteria and were analysed statistically. Results: The outcome of the treatment after 28 days showed high statistical significance in parameters like color (vrana) ,wound bed , sourrounding skin, type and amount of discharge from the wound and pain . Conclusion: Both these treatments showed reduction in symptoms but Group B in which Durvadi Ghrita was used showed better results. It can be concluded that Durvadi Ghrita is very effective in the management of Shuddha Vrana when compared to Povidone Iodine.