Beta-caryophyllene inhibits the permeability of the blood–brain barrier in MPTP-induced parkinsonism
These results highlight the role of CB2 as a therapeutic target for PD, suggesting that its activation may ameliorate PD-related BBB disruption and oxidative stress, reducing the selective death of dopaminergic neurons.
Authors
- V. Chaparro‐Huerta (ORCID: https://orcid.org/0000-0001-8647-5071)
- Luis Javier Ramírez-Jirano (ORCID: https://orcid.org/0000-0002-2299-6721)
- Ana Raquel Ramos-Molina (ORCID: https://orcid.org/0000-0002-9907-8937)
- Aldo Rafael Tejeda-Martínez (ORCID: https://orcid.org/0000-0002-0220-5523)
- Juan Manuel Viveros–Paredes (ORCID: https://orcid.org/0000-0002-7532-5614)
- Mario Eduardo Flores-Soto (ORCID: https://orcid.org/0000-0002-5194-8569)
- María Fernanda Urmeneta-Ortíz (ORCID: https://orcid.org/0009-0007-9546-2708)
Institutions
- Mexican Social Security Institute (MX)
- Universidad de Guadalajara (MX)
- Secretaría de Salud de Jalisco (MX)
Publication Details
- Journal
- Neurología (English Edition)
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1016/j.nrleng.2025.02.003
- Citations
- 1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39