Adenosine A2A Receptor Activation Alleviated Disease of Mice with Systemic Candida albicans Infection by Regulating Macrophage Function
Activation of adenosine-A2AR axis promoted macrophage M2 polarization, enhanced host defense against systemic <i>C. albicans</i> infection, and alleviated candidiasis. A2AR activation could be considered as a potential therapeutic strategy in candidemia.
Authors
- Zhaowei Gao (ORCID: https://orcid.org/0000-0003-4477-0966)
- Ke Dong (ORCID: https://orcid.org/0000-0002-9773-6350)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-1229-9033)
- Yan Liu (ORCID: https://orcid.org/0000-0003-0906-2606)
- Lan Yang
- Ming Yang (ORCID: https://orcid.org/0000-0002-4191-5640)
- Xianan Wu
Institutions
- Tang Du Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/jir.s501546
- Citations
- 1
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.12