Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection
Objective: To study the therapeutic effect of the Extract of Wuwei Xiaodu Drink on spinal infection and provide the scientific basis for clinical application. Methods: By establishing a rabbit model of spinal infection, this paper observed and analyzed the changes in body mass before and after the intervention and the comparison of inflammation-related factors and blood leukocyte counts among the three groups. Results: There was a significant difference in the changes in body mass of rabbits before and after intervention in the experimental group, control group and blank group (P < 0.05); there was no statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the control group (P > 0.05), and there was a statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the blank group (P < 0.05). Conclusion: The Extract of Wuwei Xiaodu Drink can play a protective role by regulating the level of inflammatory factors in blood routine leukocyte count and reducing the inflammatory reaction in the spinal cord injury area.
Authors
- Xiuping Li (ORCID: https://orcid.org/0000-0001-7599-8846)
- Qin Wang (ORCID: https://orcid.org/0000-0002-4955-1490)
- Jianhua Zhang (ORCID: https://orcid.org/0000-0002-4529-8619)
- Zhang Qiang (ORCID: https://orcid.org/0000-0002-7608-1156)
- Ying Zhan (ORCID: https://orcid.org/0000-0001-8472-7191)
- Zheng Song
Institutions
- Shandong University (CN)
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Journal of Clinical and Nursing Research
- Published
- 2025-03-06
- DOI
- https://doi.org/10.26689/jcnr.v9i2.9770
- Primary Topic
- Medical Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00