Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection

Objective: To study the therapeutic effect of the Extract of Wuwei Xiaodu Drink on spinal infection and provide the scientific basis for clinical application. Methods: By establishing a rabbit model of spinal infection, this paper observed and analyzed the changes in body mass before and after the intervention and the comparison of inflammation-related factors and blood leukocyte counts among the three groups. Results: There was a significant difference in the changes in body mass of rabbits before and after intervention in the experimental group, control group and blank group (P < 0.05); there was no statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the control group (P > 0.05), and there was a statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the blank group (P < 0.05). Conclusion: The Extract of Wuwei Xiaodu Drink can play a protective role by regulating the level of inflammatory factors in blood routine leukocyte count and reducing the inflammatory reaction in the spinal cord injury area.

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Publication Details

Journal
Journal of Clinical and Nursing Research
Published
2025-03-06
DOI
https://doi.org/10.26689/jcnr.v9i2.9770
Primary Topic
Medical Research and Treatments
Type
article
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article

Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection

Xiuping Li, Qin Wang, Jianhua Zhang, Zhang Qiang et al.
Journal of Clinical and Nursing Research
Medical Research and Treatments
article

Exploration of the Value of Extract of Wuwei Xiaodu Drink on Rabbit Model of Spinal Infection

Xiuping Li, Qin Wang, Jianhua Zhang, Zhang Qiang, Ying Zhan, Zheng Song
article en

Abstract

Objective: To study the therapeutic effect of the Extract of Wuwei Xiaodu Drink on spinal infection and provide the scientific basis for clinical application. Methods: By establishing a rabbit model of spinal infection, this paper observed and analyzed the changes in body mass before and after the intervention and the comparison of inflammation-related factors and blood leukocyte counts among the three groups. Results: There was a significant difference in the changes in body mass of rabbits before and after intervention in the experimental group, control group and blank group (P < 0.05); there was no statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the control group (P > 0.05), and there was a statistically significant difference in calcitoninogen, C-reactive protein and routine blood leukocyte counts between the experimental group and the blank group (P < 0.05). Conclusion: The Extract of Wuwei Xiaodu Drink can play a protective role by regulating the level of inflammatory factors in blood routine leukocyte count and reducing the inflammatory reaction in the spinal cord injury area.

Journal of Clinical and Nursing ResearchVol. 9(2)
Shandong University (CN), Shanghai Public Health Clinical Center (CN)
Good health and well-being
Openalex Percentile: Top 94%
Medical Research and Treatments
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