Dissecting Causal Relationship Among Immune Cells, Plasma Metabolites and Coronary Atherosclerosis: A Mendelian Randomization Study
Key immune cell phenotypes and plasma metabolites were linked to coronary atherosclerosis. The roles of 3-hydroxy-2-ethylpropionate and trans-2-hexenoylglycine in regulating B-cell function suggest potential therapeutic targets for prevention and treatment.
Authors
- Jin‐Kun Wen (ORCID: https://orcid.org/0000-0002-8453-4549)
- Haoyang Zheng (ORCID: https://orcid.org/0000-0001-6835-8242)
- Qi Cao (ORCID: https://orcid.org/0000-0001-6901-8928)
- Jingyu Sun (ORCID: https://orcid.org/0000-0001-7231-9158)
- Jiajing Liu
- Bin Zheng (ORCID: https://orcid.org/0000-0001-8429-5384)
- S. Qian
- Jie Song (ORCID: https://orcid.org/0009-0007-0282-9962)
Institutions
- Hebei Medical University (CN)
Publication Details
- Journal
- ImmunoTargets and Therapy
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/itt.s508042
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00