Management of Renal Salt-Wasting Disease in a Patient

Renal salt-wasting disease (RSWD) is a rare process characterized by hyponatremia and extracellular fluid volume depletion. This case study details the management of a patient with severe hyponatremia found to be secondary to RSWD. We aim to highlight the challenges in diagnosing, treating, and monitoring RSWD in the intensive care setting, including differentiating RSWD from other hyponatremic pathologies with similar clinical presentations. In this case, we achieved treatment success using multi-modal therapy that included sodium chloride tablets, fludrocortisone, and ibuprofen to restore eunatremia.