ENDOMETRIAL METASTASIS OF BREAST CANCER: A CASE REPORT AND REVIEW OF THE LITERATURE

Endometrial metastasis of breast cancer is an exceptionally rare occurrence, with limited cases reported in the literature. While breast cancer commonly metastasizes to bones, lungs, liver, and brain, endometrial involvement remains unusual and diagnostically challenging. This case report describes a 48-year-old female with a significant family history of breast cancer, presenting with locally advanced left breast carcinoma and widespread metastases, including brain, bone, and endometrial involvement. Initial imaging and histopathology suggested a primary endometrial tumor, but immunohistochemical analysis confirmed metastatic breast carcinoma. This case highlights the diagnostic complexities of distinguishing primary endometrial malignancies from metastatic lesions, particularly in advanced breast cancer. The patients aggressive disease progression, marked by complications such as lesional epilepsy and hydronephrosis, underscores the need for a multidisciplinary approach to diagnosis and management. This article reviews the literature on endometrial metastases of breast cancer, emphasizing diagnostic challenges, therapeutic implications, and prognostic considerations.