Study On Early And Late Gene Expression In Mesenchymal Stem Cells Using HA/ Cuo Based Scaffold In Bone Regeneration

Introduction Mesenchymal stem cells (MSCs) are multipotent cells derived from the bone marrow that migrate to injury sites, promote bone regeneration, and modulate immune responses. Gene expression, the process by which genetic information is transformed into functional proteins, is fundamental to tissue regeneration. Current regenerative strategies aim to direct cells with regenerative potential to repopulate lesions, promoting new cementum formation and connective tissue attachment.In periodontal tissue regeneration, the differentiation of mesenchymal cells into cementoblasts is critical for forming new cementum, facilitating the attachment of periodontal ligament fibers to the root and alveolar bone