Antibacterial activity and mechanism of Sodium houttuyfonate against heteroresistant Pseudomonas aeruginosa
Our study demonstrated that Sodium houttuyfonate and Meropenem exhibited synergistic inhibition against heteroresistant <i>Pseudomonas aeruginosa</i>, and that Sodium houttuyfonate may achieve its inhibitory effect by inhibiting bacterial biofilm formation, inhibiting motility, and down-regulating related genes.
Authors
- Cuiyu Tan
- Lingqing Xu (ORCID: https://orcid.org/0000-0003-4630-7721)
- Dan Wang
- Tongtong Zhang (ORCID: https://orcid.org/0000-0003-1462-9849)
- Shuqiang Huang
- Xiaojun Yuan
- Zhihong Li
- Ziqi Wang
Institutions
- First People's Hospital of Foshan (CN)
- Qingzhou City People's Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3389/fmicb.2025.1523182
- Citations
- 1
- Primary Topic
- Nephrotoxicity and Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 1.36