Clinical characteristics, molecular epidemiology and mechanisms of colistin heteroresistance in Enterobacter cloacae complex
Colistin heteroresistance showed species-dependent variations in levels and prevalence rates. The colistin-heteroresistant mechanisms were complex, involving coordinated regulation of multiple genes. These results highlighted the need for tailored antimicrobial stewardship. In addition, the development of direct, reliable and rapid clinical methods for detecting heteroresistance is essential for improving infection management and prevention.
Authors
- Xushan Liang
- Yanhua Liang (ORCID: https://orcid.org/0000-0001-8315-1661)
- Wenzhang Long
- Mingjing Liao
- Chunli Wei (ORCID: https://orcid.org/0000-0002-5966-283X)
- Xue Gong
- Jianmin Wang (ORCID: https://orcid.org/0000-0001-6841-7943)
- Yang Yang (ORCID: https://orcid.org/0000-0002-3516-0683)
- Xiaoli Zhang (ORCID: https://orcid.org/0000-0001-7854-0515)
- Jie Li (ORCID: https://orcid.org/0000-0002-9623-9213)
- Jin Wang (ORCID: https://orcid.org/0000-0003-0678-7628)
- Jisheng Zhang
- Shijian Chen
- Kaixin Yu (ORCID: https://orcid.org/0009-0007-1776-1649)
- Jiming Wu
Institutions
- Jiamusi University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3389/fcimb.2025.1536058
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.77