HCC-derived CX3CL1 affects hepatocellular carcinoma prognosis and CX3CR1 + MDSC infiltration
These findings highlight the possible involvement of CX3CL1 in HCC progression via MDSC recruitment, suggesting that it is a promising therapeutic target for promoting antitumor immunity. Further studies are needed to confirm these findings and explore potential therapeutic strategies.
Authors
- Yidan Lou (ORCID: https://orcid.org/0000-0001-9703-567X)
- Xiaoling Zhang (ORCID: https://orcid.org/0009-0004-1642-0808)
- Xu Chang (ORCID: https://orcid.org/0009-0002-2345-7807)
- Song Zheng (ORCID: https://orcid.org/0000-0003-0859-0968)
Institutions
- Shandong Tumor Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Shandong First Medical University (CN)
- Hangzhou Cancer Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s40001-025-02410-z
- Citations
- 5
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 5.23