Impact of oral precancerous lesions on oral cancer development in patients with oral lichen planus: a retrospective cohort study of 318 oral lichen planus patients
The current study indicates that the presence of OPLs, including histologically confirmed verrucous hyperplasia and varying degrees of oral dysplasia, is associated with an increased risk of oral cancer development in patients with OLP. Further research is needed to elucidate the underlying molecular mechanisms linking OLP, OPL, and oral cancer occurrence.
Authors
- Chien‐Chin Chen (ORCID: https://orcid.org/0000-0001-9599-0884)
- Wan‐Ting Huang (ORCID: https://orcid.org/0000-0002-4344-9567)
- Hsun‐Yu Huang
- Yu-Cheng Chu (ORCID: https://orcid.org/0000-0001-6255-3071)
- Pei-Yu Lin
Institutions
- National Chung Hsing University (TW)
- Chia-Yi Christian Hospital (TW)
- Kaohsiung Veterans General Hospital (TW)
- Chia Nan University of Pharmacy and Science (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- Frontiers in Oral Health
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3389/froh.2025.1560600
- Citations
- 2
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.93