Sustainable nanophytosome-based therapies against multidrug-resistant Escherichia coli in urinary tract infections: an in Vitro and in vivo study
Our research introduces a cost-effective and innovative approach to addressing UTIs caused by MDR E. coli by the use of rosemary oil, a natural antimicrobial agent encapsulated in nanophytosomes. This strategy not only demonstrates proven therapeutic efficacy in UTI animal models but also promotes the adoption of sustainable medical approaches. CS-nanophytosomes provides a sustainable alternative therapeutic option to combat MDR UTIs.
Authors
- Heba Essam Sedky Ahmed
- Sarah M. Abdelhamid (ORCID: https://orcid.org/0000-0001-6550-3643)
- Wessam F. El-Hadidy (ORCID: https://orcid.org/0000-0003-4975-8755)
- Ming Ming Wen (ORCID: https://orcid.org/0000-0002-1046-2167)
- Ibrahim A. Abdelwahab (ORCID: https://orcid.org/0000-0002-8279-4363)
- Rania Abozahra (ORCID: https://orcid.org/0000-0002-2357-7932)
- Kholoud Baraka (ORCID: https://orcid.org/0000-0001-8544-8426)
Institutions
- Pharos University in Alexandria (EG)
- Damanhour University (EG)
- Alexandria University (EG)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s12951-024-03006-1
- Citations
- 3
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 1.55