LINC00968 accelerates osteogenic differentiation of bone marrow mesenchymal stem cells via the miR-17-5p/STAT3 axis
Our results indicate that LINC00968 downregulation is a diagnostic biomarker for OP, facilitating osteogenic differentiation and inhibiting apoptosis via miR-17-5p/STAT3 axis, suggesting a new therapeutic target for OP progression.
Authors
- Shanglong Ning (ORCID: https://orcid.org/0009-0003-7185-4513)
- Yang Chen (ORCID: https://orcid.org/0000-0002-6027-7955)
- Hui Zhu (ORCID: https://orcid.org/0000-0003-0348-5560)
Institutions
- Tianjin University (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Tianjin Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s13018-025-05627-0
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- China Postdoctoral Science Foundation