Targeting glycolysis in esophageal squamous cell carcinoma: single-cell and multi-omics insights for risk stratification and personalized therapy
This research emphasizes the crucial role of glycolysis in ESCC progression a well as immune modulation, offering a novel glycolysis-related risk score model with significant prognostic and therapeutic implications. These findings provide a basis for risk-based stratification and tailored therapeutic strategies, advancing precision medicine in ESCC.
Authors
- Xiao Hu (ORCID: https://orcid.org/0000-0003-1128-4099)
- Yan Wang (ORCID: https://orcid.org/0000-0002-4006-5859)
- Chenfang Wang (ORCID: https://orcid.org/0000-0003-2546-6918)
- Y. Shi (ORCID: https://orcid.org/0009-0003-2225-1951)
Institutions
- Chengdu Medical College (CN)
- First Affiliated Hospital of Chengdu Medical College (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3389/fphar.2025.1559546
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01