Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

In this report, we present three cases of refractory isolated non-infectious uveitis successfully treated with JAK-i. This is the first report on the use of baricitinib and upadacitinib in this context. Our findings suggest that alternative use of JAK-i, apart from tofacitinib alone, may be an effective treatment option for such patients.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-03-06
DOI
https://doi.org/10.3389/fphar.2025.1509404
Citations
1
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
1.71
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article

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

Nataša Vidović Valentinčič, Matija Tomšič, Pia Klobučar, Polona Jaki Mekjavič et al.
1 citations
Frontiers in Pharmacology
Ocular Diseases and Behçet’s Syndrome
1.71
article

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

Nataša Vidović Valentinčič, Matija Tomšič, Pia Klobučar, Polona Jaki Mekjavič, Nina Vidic Krhlikar
article en
1 citations

Abstract

In this report, we present three cases of refractory isolated non-infectious uveitis successfully treated with JAK-i. This is the first report on the use of baricitinib and upadacitinib in this context. Our findings suggest that alternative use of JAK-i, apart from tofacitinib alone, may be an effective treatment option for such patients.

Frontiers in PharmacologyVol. 16
University of Ljubljana (SI), Ljubljana University Medical Centre (SI), Jožef Stefan Institute (SI)
Good health and well-being
Openalex Percentile: Top 21%
Ocular Diseases and Behçet’s Syndrome
1.71
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Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series — Nataša Vidović Valentinčič, Matija Tomšič, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS