LncRNA H19 overexpression protects against acute kidney injury after cardiopulmonary bypass via activating Pink1/Parkin-mediated mitophagy
These findings suggest that H19 overexpression may protect against CPB-AKI by activating Pink1/Parkin-mediated mitophagy and decreasing inflammatory responses and cellular apoptosis. Thus, H19 overexpression might be a promising therapeutic target for treating CPB-AKI.
Authors
- Mingru Zhang (ORCID: https://orcid.org/0000-0002-4514-9824)
- Bingyang Ji (ORCID: https://orcid.org/0000-0002-1410-6901)
- Yafan Bai
- Dinghao Xue (ORCID: https://orcid.org/0000-0002-9727-4133)
- Guyan Wang (ORCID: https://orcid.org/0000-0003-3098-5472)
- Yue Zhang (ORCID: https://orcid.org/0000-0003-4597-9964)
- Yimeng Chen (ORCID: https://orcid.org/0000-0002-0588-8307)
- Tianlong Wang (ORCID: https://orcid.org/0000-0003-1887-8236)
- Min Liu (ORCID: https://orcid.org/0000-0002-4952-2577)
- Yingjie Du (ORCID: https://orcid.org/0000-0003-4484-5024)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1097/cm9.0000000000003552
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87