Livedoid Vasculopathy

Livedoid Vasculopathy (LV) is an uncommon thrombotic occlusive vasculopathy presenting with chronic relapsing-remitting painful skin ulcerations, predominantly affecting the feet and ankles bilaterally. LV can be idiopathic or secondary to varied causes including endothelial, rheological, haemostatic or fibrinolytic pathologies. We describe three LV cases here in with a review of the current literature on its epidemiology, risk factors and management options. It is of quite clinical significance to differentiate the LV from vasculitic disorders, as the management of the latter being based on immunosuppression, whereas LV treatment is mostly based around anticoagulant or antiplatelet therapy. Livedoid Vasculopathy (LV) is an uncommon thrombotic occlusive vasculopathy presenting with chronic relapsing-remitting painful skin ulcerations, predominantly affecting the feet and ankles bilaterally. LV can be idiopathic or secondary to varied causes including endothelial, rheological, haemostatic or fibrinolytic pathologies. We describe three LV cases here in with a review of the current literature on its epidemiology, risk factors and management options. It is of quite clinical significance to differentiate the LV from vasculitic disorders, as the management of the latter being based on immunosuppression, whereas LV treatment is mostly based around anticoagulant or antiplatelet therapy.