Pharmacological Evaluation of Amorphophalli rhizoma to Inhibit the Progression of Estrogen Receptor+ (ER+) Breast Cancer by Modulating the PI3K/AKT Cell Signaling Pathway
Additionally, APR-EA might increase the expression of P21 and Bax proteins, which are associated with cell cycle arrest and apoptosis. Overall, these effects contribute to the anti-ER+ breast cancer properties of APR-EA.
Authors
- Liaqat Hussain (ORCID: https://orcid.org/0000-0001-7171-5917)
- Qinghong Yu (ORCID: https://orcid.org/0000-0002-7326-7609)
- Jiaqing Song (ORCID: https://orcid.org/0000-0002-8281-407X)
- Huiqi Li (ORCID: https://orcid.org/0000-0002-1127-0829)
- Hanyue Ding (ORCID: https://orcid.org/0000-0001-9977-0985)
- Ying Jin (ORCID: https://orcid.org/0000-0002-8811-2204)
- Yi‐An Chen (ORCID: https://orcid.org/0000-0002-8002-6256)
- Hongting Wu (ORCID: https://orcid.org/0009-0006-3730-4560)
- Xiufei Gao (ORCID: https://orcid.org/0000-0002-3188-2216)
Institutions
- Zhejiang Chinese Medical University (CN)
- Government College University, Faisalabad (PK)
- Zhejiang DongFang Vocational and Technical College (CN)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2025-03-05
- DOI
- https://doi.org/10.2174/0115680096360994250106082347
- Citations
- 1
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 0.81