Paeonia suffruticosa Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway
In summary, PSAE attenuates UV-induced oxidative damage, genetic damage, and collagen degradation associated with photoaging by modulating the IRS/PI3K/FOXO signaling pathway. This study elucidated the mechanism through which PSAE, thereby providing strong support for its application in cosmetic anti-aging formulations.
Authors
- Junxi Liu (ORCID: https://orcid.org/0000-0001-6490-5704)
- Feifei Wang (ORCID: https://orcid.org/0000-0002-2351-6873)
- Liu Y (ORCID: https://orcid.org/0000-0001-8568-623X)
- Hongyu Ma (ORCID: https://orcid.org/0000-0002-8689-5970)
- Liping Qu (ORCID: https://orcid.org/0000-0001-6469-218X)
- Ye Yuan (ORCID: https://orcid.org/0000-0001-9628-6944)
Institutions
- Yunnan Botanee Biotechnology Group Co.
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3389/fphar.2025.1520392
- Citations
- 6
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 12.03