Assessment of Hepatoprotective Potential of Dendrobium bicameratum, a Bryophyte from Eastern Ghats, Odisha

An investigation was conducted to assess the hepatoprotective potential of hydroalcoholic andaqueous extracts of Dendrobium bicameratum in Wistar rats with carbon tetrachloride (CCl4)-induced hepaticdamage. The extent of liver injury was evaluated by measuring serum biomarkers, including SGOT, SGPT,total albumin, total protein, IL-1β, IL-6, and TNF-α. Administration of hydroalcoholic (HADBM) and aqueous(ADBM) extracts at 200 mg/kg, as well as silymarin (100 mg/kg), demonstrated significant (P < 0.05)hepatoprotective effects by reducing the levels of serum hepatoprotective and inflammatory mediators. Thesefindings suggest that Dendrobium bicameratum extracts exhibit pronounced hepatic protection, comparableto the standard hepatoprotective agent silymarin.