10-Hydroxydec-2-enoic acid reduces vascular smooth muscle cell inflammation via interacting with Toll-like receptor 4
The present work of 10-HDA, for the first time, revealed its ability to alleviate VSMC inflammation by targeting TLR4 and therefore modulate the downstream inflammatory participants. Our data will cast light on the utilization of 10-HDA in VSMC inflammation-related vascular disorders.
Authors
- Lei Zeng (ORCID: https://orcid.org/0000-0001-6517-8772)
- Yongqing Wang
- Yanyan Wang (ORCID: https://orcid.org/0000-0003-0797-3895)
- Pei Fan (ORCID: https://orcid.org/0000-0001-8067-0896)
- Zhiqiang Chen (ORCID: https://orcid.org/0000-0003-4209-7181)
- Feng Jia
- Jingxian Jin
- Huaijian Tang
- Li Zhang (ORCID: https://orcid.org/0009-0005-3944-4113)
Institutions
- Henan University of Technology (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1016/j.phymed.2025.156534
- Citations
- 6
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 4.78
Funders
- Henan University of Technology