ACLY Promotes Cardiac Fibrosis via the Regulation of DNL and Histone Acetylation
Our findings demonstrate that ACLY plays an important role in maladaptive cardiac fibrosis. ACLY could be a novel therapeutic target to prevent the development of heart failure.
Authors
- Makoto Nishimori (ORCID: https://orcid.org/0000-0002-1366-9948)
- Naoya Kuwahara
- Hiromasa Otake (ORCID: https://orcid.org/0000-0001-9953-0551)
- Takeshi Yoshida (ORCID: https://orcid.org/0000-0002-4695-5377)
- Kenta Kaneshiro (ORCID: https://orcid.org/0000-0003-2161-7168)
- Takuo Emoto (ORCID: https://orcid.org/0000-0001-7425-4087)
- Masakazu Shinohara (ORCID: https://orcid.org/0000-0001-8724-0071)
- Terunobu Fukuda (ORCID: https://orcid.org/0000-0002-4073-6763)
- Manabu Nagao (ORCID: https://orcid.org/0000-0001-7269-4513)
- Seimi Satomi‐Kobayashi (ORCID: https://orcid.org/0000-0003-4656-260X)
- Ryuji Toh (ORCID: https://orcid.org/0000-0002-7204-6695)
- Tatsuro Ishida (ORCID: https://orcid.org/0000-0002-1724-0057)
- Ken-ichi Hirata
Institutions
- Hyogo University of Health Sciences (JP)
- IONICS Mass Spectrometry (Canada) (CA)
- Norwegian Womens Public Health Association (NO)
- Kobe University (JP)
Publication Details
- Journal
- Hypertension
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1161/hypertensionaha.124.24088
- Citations
- 6
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 8.33